longevity and reverse aging

Blood Plasma Protein Profile as a Biomarker of Aging - December 7, 2015

I think you'll find this open access work on a potential biomarker of aging to be interesting; the researchers use it to assess the results of different lifestyle choices, finding that some of those known to shorten life expectancy produce a higher measure of biological age in their biomarker.

This seems a small step closer to validating the usefulness of such biomarkers. A number of research groups are presently developing biomarkers of aging based on characteristic patterns of epigenetic modifications or altered protein levels.

We should expect to find common patterns because the cell and tissue damage that causes aging, and the evolved reactions to that damage, are the same in everyone. The challenge lies in identifying these common patterns amidst the complex, varied alterations that occur due to individual circumstances and environment, but solid progress has being made in recent years.

Read More:  https://www.fightaging.org/archives/2015/12/blood-plasma-protein-profile-as-a-biomarker-of-aging.php



Confirming Data for the Agelessness of Hydra - December 9, 2015

It has long been suspected that hydra, small freshwater animals, are immortal in that they do not suffer degenerative aging. In practice this means that no changes in mortality rate, reproduction rate, and measures of cellular metabolism are observed over time.

This is a highly regenerative species, with individuals capable of rebuilding themselves from fragments, and it may be the case that their constant regeneration is the source of their agelessness. Regarding that agelessness, the challenge for researchers is that verifying the lack of aging in a species is a slow statistical business of wait and see, and one can always suspect at the end of any given study that the authors did not check rigorously enough for signs of aging.

Perhaps it is there, just too slow to show up over the time allotted. Certainly there has been some back and forth debate over the last twenty years regarding what the data does or does not support. This latest research provides a set of much more robust evidence in support of hydra agelessness.

Read More https://www.fightaging.org/archives/2015/12/confirming-data-for-the-agelessness-of-hydra.php



The Latest US Life Expectancy and Mortality Figures - December 10, 2015

The mortality data for 2014 was recently published by the CDC. The popular press has been making a big deal of the fact that the statistical measure of life expectancy at birth has remained much the same these past few years.

This is something that epidemiologist S. Jay Olshansky has suggested might happen as a result of the consequences of greater obesity temporarily outweighing progress in medicine, but a few years is too short a period of time to confirm any departure from the long slow upward trend in life expectancy established over past decades.

Meanwhile we should bear in mind that present trends are the outcome of a period of development in which researchers were making no efforts to treat the causes of aging; gains in life expectancy were incidental. That is now changing, and future trends will reflect a research community increasingly involved in building therapies that target the mechanisms of aging. The past will not reflect the future, and this is a time of transition.

Read More https://www.fightaging.org/archives/2015/12/the-latest-us-life-expectancy-and-mortality-figures.php
 


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