A more immediate hazard comes from muons.  
These  subatomic particles, created when high‑energy cosmic rays strike the  upper atmosphere, constantly zip through our bodies and occasionally  damage genetic material at the cellular level. They cause many of the  spontaneous tumors that have been with us long before we started downing  charred hot dogs.
 
Then there’s the remote possibility of a near‑enough supernova  to zap our planet with lethal gamma rays. It’s a wonderfully weird  catastrophe, worthy of these darkest nights. Orion’s famous star  Betelgeuse is the nearest true peril. If it “goes supernova” the  resulting radiation would increase earthly cancers and mutations. But at  400 lightyears, it’s too distant to wipe us out.